GFP WHOLE CELL MICROBIAL BIOSENSORS:
SCALE-UP AND SCALE-DOWN EFFECTS
ON BIOPHARMACEUTICAL PROCESSES
FRANK DELVIGNE, ALISON BROGNAUX, SHANSHAN HAN, SØREN J. SØRENSEN,
AND PHILIPPE THONART
ASME Press Books, Two Park Avenue, New York, NY 10016-5990. 2013.
Two strategies are usually considered for the optimization of micro- bial bioprocesses. One involves genetic or metabolic engineering of the target microbial strains; the other is based on the chemical engineering improvement of the bioreactors and scaling-up rules. This monograph, part of a series on biomedical and nanomedical
technologies, deals with the second strategy, including several sub-100 ml
mini-bioreactor concepts and the engineering similarities between conventional stirred bioreactors and their miniature equivalents. Other concepts tackled in the monograph are the importance of the operating scale
on the interaction between fluid flow and microbial cells; the stochastic
simulation of the displacement of microbial cells along concentration
field; and experimental results gained from the physiological response of
green fluorescent protein biosensors in scale-down conditions.
60 PAGES. $89.95; ASME MEMBERS, $72; ISBN: 978-0-7918-6009-0.
TRANSITION TO RENEWABLE
Detlef Stolten and Viktor Scherer
Wiley-VCH Verlag GmbH & Co..
KgaA, Boschstrasse 12, 69469
Weinheim, Germany. 2013.
Stolten and Scherer, two leading German energy researchers, look
to a transition to renewable energy driven by concerns over global
climate change. Using a timeline of 2050 for a major CO2 reduction
in order to fulfill the United Nations global warming goal of 2 °C,
the authors draw on reports of selected energy strategies as well as
in-depth technical information on the already-existing technologies, such as solar, wind, biomass and hydro power, and those like
geothermal or hydrokinetic power that are still being developed.
The book’s focus on the whole energy system involves particular
consideration of storage technologies for the fluctuating renewable
energy input as well as an overview on transporting energy via
electrical or chemical means.
1,008 PAGES. $340. ISBN: 978-3-52733-239-7.
INTRODUCTION TO THE
CALCULUS OF VARIATIONS
AND CONTROL WITH MODERN
John A. Burns
CRC Press, Taylor & Francis
Group, 600 Broken Sound Parkway
NW, Suite 300, Boca Raton, FL 33487-2742. 2014.
Introduction to the Calculus of Variations and Control with Modern Applications provides the fundamental background required to
develop rigorous necessary conditions that are the starting points
for theoretical and numerical approaches to modern variational
calculus and control problems. The book also presents some
classical sufficient conditions and discusses the importance of
distinguishing between the necessary and sufficient conditions.
Burns develops the calculus of variations and provides complete
proofs of the main results and then explains how the ideas behind
the proofs are essential to the development of modern optimization
and control theory. The author goes on to show how optimal control
is a natural extension of the classical calculus of variations to
more complex problems.
562 PAGES. $99.95. ISBN: 978-1-4665-7139-6.